Services

LCF offers to business, clinical and research groups services for product development, process development and establishment of quality controls methods.

  • 1. GMP manufacturing of Cell Therapy and Tissue Engineering Products
    • cell isolation from tissues (bone marrow, adipose tissue, peripheral blood…)
    • set-up of primary cultures
    • long term cultures in normal and hypoxic conditions
    • large scale cell cultures
    • concentration and purification of cell-derived products (microvesicles)
  • 2. Quality control assays according to GMP standards
    • Flow cytometry for surface markers, viability, apoptosis, cell cycle, rare cells… (EuPh 2.6.29 and EuPh 2.6.24)
    • Real time PCR
    • ELISA testing for cytokine, antibody and drug dosage in biological fluids
    • Sterility testing (EuPh 2.6.1 and EuPh 2.6.27)
    • Bacteria identification
    • Endotoxin test (EuPh 2.6.14)
    • Cell based assays (clonogenic potential, invasion, proliferation, cytoxicity …)
  • 3. High quality services for research and clinical studies
    • Cell banking
    • Plasma and serum preparation
    • Cell isolation from tissue biopsies, bone marrow and peripheral blood
    • Storage of cells and biological fluids
    • Microbiological monitoring of the laboratory environment
  • 4. Consultancies ‘from R&D to ATMP’
    • LCF gives consultancies on GMP requirements and regulatory issues to clinical and research entities who need to bring up the quality of their productions to the GMP level.